T cell Immunoglobulin and Mucin Domain Containing Protein 3 (TIM-3) Inhibitors in Oncology Clinical Trials: A Review
ABSTRACT: T cell immunoglobulin and mucin domain containing protein 3 (TIM-3) is a receptor found on a multitude of immune cells and is commonly overexpressed in patients with cancer.Due to its Patient Alarms selective expression in immune cells and its preliminary efficacy in preclinical models, TIM-3 is a promising target Keypad Assembly as a tre